What are the long term effects of Herceptin?

Herceptin testimonials

Almost all treatments can cause late effects, and these late effects are specific to the treatment you received. Below is a list of some of the most common late effects. Talk to your doctor about any concerns you have about a specific late effect.

The risk of high blood pressure decreases once a person stops taking these drugs. However, the long-term effects are unknown. Survivors at increased risk for high blood pressure should work with their health care team to reduce this risk. This may include measures such as measuring blood pressure, losing weight, eating less salt, taking medications, and staying active.

Endocrine (hormone) system problems. Some types of cancer treatments can affect the endocrine system. The endocrine system includes the glands and other organs that make hormones and produce eggs or sperm. Cancer survivors who are at risk for hormone changes due to treatment should have regular blood tests to measure hormone levels.

How long does trastuzumab treatment last?

When a trastuzumab injection product is used to treat stomach cancer, it is usually given once every 3 weeks. The length of treatment depends on how well your body responds to the drug and the side effects you experience.

Which Herceptin?

A drug used alone or with other drugs to treat certain types of HER2-positive breast cancer, stomach cancer, and gastroesophageal junction cancer. It is also being studied for the treatment of other types of cancer.

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How many doses of trastuzumab?

The recommended starting dose is 8 mg/kg body weight. The recommended maintenance dose is 6 mg/kg body weight every three weeks, starting three weeks after the starting dose. Weekly schedule The recommended starting dose of Herceptin is 4 mg/kg body weight.

Pertuzumab and trastuzumab side effects

Fatigue is the most common symptom of cancer survivors. Cancer-related fatigue is a consequence of the cancer, its treatment and the side effects of treatment. Survivors often complain that they cannot overcome fatigue, no matter how much sleep they get. If you feel tired, talk to your doctor about strategies to overcome fatigue, such as exercise, relaxation techniques and energy conservation.

Steroids used to treat some cancers can increase blood glucose levels (hyperglycemia) in some patients who do not have diabetes. Although it is not clear whether these patients will develop diabetes, they are at increased risk for diabetes because their glucose levels may remain elevated after treatment ends.

Males with colorectal or genitourinary cancer who have received chemotherapy and radiation therapy have an increased risk of infertility. Chemotherapy drugs that affect male fertility include alkylating and methylating agents, vinca alkaloids, antimetabolites and platinum.

What are the effects of trastuzumab?

The most severe adverse effect of trastuzumab is cardiotoxicity, in addition to other effects such as pulmonary infiltration [9], headache, arthralgia, fatigue, nasopharyngitis, diarrhea, heartburn and nausea, vomiting, cough and edema, among others [4].

How effective is trastuzumab?

Authors’ conclusions: Trastuzumab improved overall survival and progression-free survival in patients with HER2-positive metastatic breast cancer, but also increased the risk of cardiac toxic effects such as congestive heart failure and decreased LVEF.

When is trastuzumab used?

Trastuzumab (Herceptin, others): Trastuzumab can be used to treat both early and advanced breast cancer. This drug is often given with chemotherapy, but can also be used alone (especially if chemotherapy alone has already been tried).

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Trastuzumab hair loss

Trastuzumab is an anticancer drug. It is usually used to treat a type of breast cancer called HER2 breast cancer. It may also be used to treat certain stomach or throat (esophagus) cancers that have spread.

Trastuzumab only works when the cancer cells have high levels of a protein called human epidermal growth factor receptor 2 (HER2). You will have tests first to find out if Trastuzumab is a suitable treatment for you. It may also be used to treat other types of cancer as part of a research trial.

Trastuzumab is from a group of anticancer drugs called monoclonal antibodies. Monoclonal antibodies are sometimes called targeted therapies because they work by targeting specific proteins (receptors) on the surface of cells.

Some cancers have too much of a protein called human epidermal growth factor receptor 2 (HER2) on the surface of their cells. These are called HER2-positive cancers. The extra HER2 receptors stimulate the cancer cells to divide and grow. Trastuzumab binds to the HER2 protein and blocks the receptor. This prevents the cells from dividing and growing.

How is Herceptin applied?

Herceptin is administered by subcutaneous injection (under the skin) for 2 to 5 minutes every three weeks.

How is trastuzumab administered?

HOW IS TRASTUZUMAB GIVEN? You can have Trastuzumab as a drip into a vein (intravenous infusion) or as an injection under the skin (subcutaneous). Generally, you can have it in the chemotherapy day unit. You usually have Trastuzumab every three weeks or once a week.

What type of drug is pertuzumab?

Pertuzumab injection is among a class of drugs known as monoclonal antibodies. Its action is to stop the growth of cancer cells.

Herceptin side effects

Esophageal cancer occurs when cancer cells develop in the esophagus, a long, tube-like structure that connects the throat and stomach. The esophagus, which transports swallowed food to the stomach, is part of the upper digestive system. The wall of the esophagus consists of several layers of tissue.

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In more advanced cases, part of the esophagus may be removed. In an esophagectomy, the part of the esophagus containing the tumor is removed along with nearby lymph nodes, and the remaining esophagus is reconnected to the patient’s stomach or part of the gastrointestinal (GI) tract. In an esophagogastrectomy, the diseased part of the esophagus, nearby lymph nodes, and part of the stomach are removed.

Chemotherapy: This treatment uses substances or drugs to kill cancer cells, or to stop cancer cells from dividing. Chemotherapy may be used before or after surgery for esophageal cancer. Chemotherapy is also used to help relieve symptoms when esophageal cancer has spread beyond the esophagus (metastasized).